Do take advantage of all Web-based job-hunting methods, including general job-hunting sites, industry-specific job sites, geo-graphic-specific job sites, company (employer) sites, and networking sites.
Do consider developing a job skills portfolio, which showcases everything you have to offer a prospective employer.
Do consider having multiple versions of your resume, including a traditional formatted resume, text-based (ASCII) resume, and a Web-based resume.
Don't expect to get a new job overnight; job-hunting takes time and patience. But do take some time to reflect on your strategies if you have been job-hunting for several months and have not had any success.
Do consider developing your personal brand. Self (career) branding is essential to the career advancement of job-seekers because branding helps define you and your value to current and prospective employers. Use these free personal branding and career self-marketing tools to help develop and strengthen your brand.
Don't quit your current job until you have a new job. And do give proper notice when you quit your current job.
Do make sure a potential employer can reach you. Provide your home phone, work phone (if you can handle the calls discretely), cell phone, and email. And do make sure that your voicemail (or user name for e-mail) is professional.
Do prepare and practice for your job interviews. And do be sure and ask questions at the interview.