The Indians will designate Derek Lowe for assignment and call up Corey Kluber from Triple-A Columbus.
Lowe started the season 6-1 but has struggled since. In his last three starts Lowe has given up 20 earned runs in 11.1 innings for an ERA of 15.88. Overall on the season Lowe is 8-10 with a 5.52 ERA.
The Indians acquired Lowe from Atlanta in the offseason.
Kluber will make his major league debut on Thursday against the Royals. He went 11-7 with a 3.59 ERA with 128 strikeouts in Columbus.