Guardians vs. Cardinals Predictions & Picks: Odds, Moneyline, Spread - May 26

Friday's contest features the St. Louis Cardinals (23-29) and the Cleveland Guardians (21-28) clashing at Progressive Field in what is expected to be a close matchup, with a projected 5-3 victory for the Cardinals according to our computer prediction. Game time is at 7:10 PM ET on May 26.

This contest's pitching matchup is set, as the Guardians will send Shane Bieber (3-3) to the mound, while Matthew Liberatore (1-0) will answer the bell for the Cardinals.

Guardians vs. Cardinals Game Info & Odds

• When: Friday, May 26, 2023 at 7:10 PM ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: BSGL
• Live Stream: Watch this game on Fubo!

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Guardians vs. Cardinals Score Prediction

Our pick for this matchup is Cardinals 5, Guardians 4.

Total Prediction for Guardians vs. Cardinals

• Total Prediction: Over 7.5 runs

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Explore More About This Game

Guardians Performance Insights

• In five games as the favorite over the last 10 matchups, the Guardians have a record of 2-3.
• Cleveland and its opponents have combined to hit the over three times in its last 10 games with a total.
• The Guardians did not cover its most recent game with a spread.
• The Guardians have been favorites in 28 games this season and won 13 (46.4%) of those contests.
• Cleveland is 13-15 this season when entering a game favored by -115 or more on the moneyline.
• The moneyline for this contest implies a 53.5% chance of a victory for the Guardians.
• Cleveland has scored 169 runs (just 3.4 per game) this season, which ranks last in MLB.
• The Guardians' 3.87 team ERA ranks ninth among all MLB pitching staffs.

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Guardians Schedule